건국대학교병원

메일 프린트

의료진 소개

이계영 정밀의학폐암센터장 [ 호흡기-알레르기내과, 정밀의학폐암센터 ]

폐암, 폐결절

외래진료 외래진료 특수클리닉 특수클리닉

진료일정 05

진료일정(날짜, 오전, 오후)
날짜
날짜
오전
오후

논문

Lee KY. Final Report on Real-World Effectiveness of Sequential Afatinib and Osimertinib in EGFR Positive Advanced Non-Small Cell Lung Cancer: Updated Analysis of the RESET Study. Cancer Research and Treatment. 2023 Oct;55(4):1152-70.
Kim IA, Hur JY, Kim HJ, Kim WS, Lee KY. A prospective phase 2 study of expeditious EGFR genotyping and immediate therapeutic initiation through extracellular vesicles (EV)-based bronchoalveolar lavage fluid (BALF) liquid biopsy in advanced NSCLC patients. Translational Lung Cancer Research. 2023 Jul;12(7):1425-35.
Lee KY. Adjuvant Osimertinib for Resected EGFR-Mutated Stage IB-IIIA Non-Small-Cell Lung Cancer: Updated Results From the Phase III Randomized ADAURA Trial. Journal of Clinical Oncology. 2023 Apr 1;41(10):1830-40.
Lee KY. Real-World Study of Osimertinib in Korean Patients with Epidermal Growth Factor Receptor T790M Mutation-Positive Non-Small Cell Lung Cancer. Cancer Research and Treatment. 2023 Jan;55(1):112-22.
Lee KY. A phase II, multicenter study of lazertinib as consolidation therapy in patients with locally advanced, unresectable, EGFR mutation-positive non-small cell lung cancer (stage III) who have not progressed following definitive, platinum-based, chemoradiation therapy (PLATINUM trial). Thoracic Cancer. 2022 Dec;13(23):3431-5.
Lee KY, Koh YC, Moon WJ. Time optimization of gadobutrol-enhanced brain MRI for metastases and primary tumors using a dynamic contrast-enhanced imaging. BMC Medical Imaging. 2022 Oct 17;22:180.
Kim IA, Kim HJ, Kim WS, Heo JY, Lee KY. Extracellular Vesicle-Based Bronchoalveolar Lavage Fluid Liquid Biopsy for EGFR Mutation Testing in Advanced Non-Squamous NSCLC. Cancers. 2022 Jun;14(11):2744.
Lee KY. Health-Related Quality of Life Outcomes in Patients with Resected Epidermal Growth Factor Receptor-Mutated Non-Small Cell Lung Cancer who underwent Adjuvant Osimertinib in the phase III ADAURA trial. Clinical Cancer Research. 2022 Jun 1;28(11):2286-96.
Lee KY. First-line Afatinib in Patients With Non-small-cell Lung Cancer With Uncommon EGFR Mutations in South Korea. Anticancer Research. 2022 Mar;42(3):1615-22.
Lee KY. Postoperative Chemotherapy Use and Outcomes From ADAURA: Osimertinib as Adjuvant Therapy for Resected EGFR-Mutated NSCLC. Journal of Thoracic Oncology. 2022 Mar;17(3):423-33.
Lee KY. Multicenter real-world data of patients harboring rare mutations other than EGFR or ALK in advanced or metastatic non-small cell lung cancer. Thoracic Cancer. 2022 Feb;13(3):380-5.
Lee KY. Real-world experience of afatinib as first-line therapy for advanced EGFR mutation-positive non-small cell lung cancer in Korea. Translational Lung Cancer Research. 2021 Dec;10(12):4353-67.
Lee KY. Expert consensus on perioperative immunotherapy for local advanced non-small cell lung cancer. Translational Lung Cancer Research. 2021 Sep;10(9):3713-36.
Lee KY. Sequential treatment of afatinib and osimertinib or other regimens in patients with advanced non-small-cell lung cancer harboring EGFR mutations: Results from a real-world study in South Korea. Cancer Medicine. 2021 Sep;10(17):5809-22.
Hur JY, Lee KY. Characteristics and Clinical Application of Extracellular Vesicle-Derived DNA. Cancers. 2021 Aug;13(15):3827.
Kim IA, Kim WS, Lee KY. ASO Author Reflections: CTNNB1 and Fusion Genes as Predictors for Recurrence in Resected Early-Stage Lung Adenocarcinoma. Annals of Surgical Oncology. 2021 Jul;28(7):3994-95.
Kim IA, Kim HJ, Lee SE, Hur JY, Hwang JJ, Lee SA, Lee KY, Kim WS. Targeted Next-Generation Sequencing Analysis for Recurrence in Early-Stage Lung Adenocarcinoma. Annals of Surgical Oncology. 2021 Jul;28(7):3983-93.
Kim IA, Kim HJ, Lee SA, Hwang JJ, Kim WS, Hur JY, Lee KY. Targeted Next-Generation Sequencing Analysis Predicts the Recurrence in Resected Lung Adenocarcinoma Harboring EGFR Mutations. Cancers. 2021 Jul;13(14):3632.
Lee KY. Detection of epidermal growth factor receptor (EGFR) mutations from preoperative circulating tumor DNA (ctDNA) as a prognostic predictor for stage I-III non-small cell lung cancer (NSCLC) patients with baseline tissue EGFR mutations. Translational Lung Cancer Research. 2021 Jul;10(7):3213-25.
Lee KY. Clinical impact of rebiopsy among patients with epidermal growth factor receptor-mutant lung adenocarcinoma in a real-world clinical setting. Thoracic Cancer. 2021 Mar;12(6):890-8.
Lee SE, Heo J, Lee KY, Kim WS, Kim HJ, Kim IA. Genomic profiling of extracellular vesicle-derived DNA from bronchoalveolar lavage fluid of patients with lung adenocarcinoma. Translational Lung Cancer Research. 2021 Jan;10(1):104-16.
Lee KY. Whole exome sequencing (WES) analysis of transformed small cell lung cancer (SCLC) from lung adenocarcinoma (LUAD). Translational Lung Cancer Research. 2020 Dec;9(6):2428-39.
Lee KY. Osimertinib in Resected EGFR-Mutated Non-Small-Cell Lung Cancer. New England Journal of Medicine. 2020 Oct 29;383(18):1711-23.
Hur JY, Lee JS, Kim IA, Kim HJ, Kim WS, Lee KY. Extracellular vesicle-based EGFR genotyping in bronchoalveolar lavage fluid from treatment-naive non-small cell lung cancer patients. Translational Lung Cancer Research. 2019 Dec;8(6):1051-60.
Lee JS, Kim HJ, Kim WS, Heo JY, Lee KY. A Case of Concurrent De Novo C797S and L858R EGFR Mutation Detected in Stage IA Non-Small Cell Lung Cancer Patient. Journal of Thoracic Oncology. 2017 Nov;12(11):e179-81.
Lee KY. Assessment of EGFR mutation status using cell-free DNA from bronchoalveolar lavage fluid. Clinical Chemistry and Laboratory Medicine. 2017 Oct;55(10):1489-95.
Lee KY. Randomized Phase III Study of Docetaxel Plus Cisplatin Versus Pemetrexed Plus Cisplatin as First-line Treatment of Nonsquamous Non-Small-cell Lung Cancer: A TRAIL Trial. Clinical Lung Cancer. 2017 Jul;18(4):e289-96.
Kim IA, Kim SJ, You KH, Lee KY, Koh HK, Kim HJ. Malignant tracheal necrosis and fistula formation following palliative chemoradiotherapy: a case report. Journal of Thoracic Disease. 2017 May;9(5):E402-7.
Kim HJ, Jang SH, Ryu JS, Lee JE, Kim YC, Lee MK, Jang TW, Lee SY, Nakamura H, Nishikata N, Mori M, Noguchi Y, Miyano H, Lee KY. The performance of a novel amino acid multivariate index for detecting lung cancer: A case control study in Korea. Lung Cancer. 2015 Dec;90(3):522-7 .
Kim AR, Yoo KH, Lee KY, Kim SJ, Kim HJ, Kim JH, Rhyu YA. A Case of Cryptogenic Organizing Pneumonia after Transarterial Chemoembolization for the Treatment of Hepatocellular Carcinoma. Tuberc Respir Dis (Seoul). 2015 Oct;78(4):469-72 .
Kim HJ, Kang SH, Chung HW, Lee JS, Kim SJ, Yoo KH, Lee KY. .Clinical features of lung adenocarcinomas with epidermal growth factor receptor mutations and miliary disseminated carcinomatosis. Thorac Cancer. 2015 Sep;6(5):629-35.
Kim HJ, Lee KY, Kim YW, Choi YJ, Lee JE, Choi CM, Baek IJ, Rho JK, Lee JC. P-glycoprotein confers acquired resistance to 17-DMAG in lung cancers with an ALK rearrangement. BMC Cancer. 2015 Jul 29;15(1):553.
Geater SL, Xu CR, Zhou C, Hu CP, Feng J, Lu S, Huang Y, Li W, Hou M, Shi JH, Lee KY, Palmer M, Shi Y, Lungershausen J, Wu YL.. Symptom and Quality of Life Improvement in LUX-Lung 6: An Open-Label Phase III Study of Afatinib Versus Cisplatin/Gemcitabine in Asian Patients With EGFR Mutation-Positive Advanced Non-small-cell Lung Cancer. J Thorac Oncol. 2015 Jun;10(6):883-9 .
Eom SY, Yim DH, Lee CH, Choe KH, An JY, Lee KY, Kim YD, Kim H. Interactions between paraoxonase 1 genetic polymorphisms and smoking and their effects on oxidative stress and lung cancer risk in a Korean population. PLoS One. 2015 Mar 5;10(3):e0119100.
Yang JC, Wu YL, Schuler M, Sebastian M, Popat S, Yamamoto N, Zhou C, Hu CP, O'Byrne K, Feng J, Lu S, Huang Y, Geater SL, Lee KY, Tsai CM, Yang JC, Wu YL, Schuler M, Sebastian M, Popat S, Yamamoto N, Zhou C, Hu CP, O'Byrne K, Feng J, Lu S, Huang Y, Geater SL, Lee KY, Tsai CM, Gorbunova V, Hirsh V, Bennouna J, Orlov S, Mok T, Boyer M, Su WC, Lee KH, Kato T, Massey D, Shahidi M, Zazulina V, Sequist LV. Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials. Lancet Oncol. 2015 Feb;16(2):141-51 .
Jung JH, Lee MY, Choi DY, Lee JW, You S, Lee KY, Kim J, Kim KP. Phospholipids of tumor extracellular vesicles stratify gefitinib-resistant nonsmall cell lung cancer cells from gefitinib-sensitive cells. Proteomics. 2015 Feb;15(4):824-35 .
Kim CH, Shin JE, Kim HJ, Lee KY. Bilateral Internal Auditory Canal Metastasis of Non-small Cell Lung Cancer. Cancer Res Treat. 2015 Jan;47(1):110-4 .
Lee KA, Lee JS, Min JK, Kim HJ, Kim WS, Lee KY. Bilateral Ovarian Metastases from ALK Rearranged Non-Small Cell Lung Cancer. Tuberc Respir Dis (Seoul). 2014 Dec;77(6):258-61 .
Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY. Freeman MR, Kim KP, Kim J. Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment. Proteomics. 2014 Aug;14(16):1845-56 .
Wu YL, Zhou C, Hu CP, Feng J, Lu S, Huang Y, Li W, Hou M, Shi JH, Lee KY, Xu CR, Massey D, Kim M, Shi Y, Geater SL. Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial. Lancet Oncol. 2014 Feb;15(2):213-22.
Kim HR, Lee JC, Kim YC, Kim KS, Oh IJ, Lee SY, Jang TW, Lee MK, Shin KC, Lee GH, Ryu JS, Jang SH, Son JW, Lee JE, Kim SY, Kim HJ, Lee KY. Clinical characteristics of non-small cell lung cancer patients who experienced acquired resistance during gefitinib treatment. Lung Cancer. 2014 Feb;83(2):252-8 .
Chung HW, Lee KY, Kim HJ, Kim WS, So Y. FDG PET/CT metabolic tumor volume and total lesion glycolysis predict prognosis in patients with advanced lung adenocarcinoma. J Cancer Res Clin Oncol. 2014 Jan;140(1):89-98.
Kim HR, Lee SY, Hyun DS, Lee MK, Lee HK, Choi CM, Yang SH, Kim YC, Lee YC, Kim SY, Jang SH, Lee JC, Lee KY. Detection of EGFR mutations in circulating free DNA by PNA-mediated PCRclamping. J Exp Clin Cancer Res. 2013 Aug 9;32(1):50..
HEE JOUNG KIM, SEO YOUNG OH, WAN SEOP KIM, SUN JONG KIM, GWANG HA YOO, WON DONG KIM and KYEYOUNG LEE. Clinical investigation of EGFR mutation detection by pyrosequencing in lung cancer patients. Oncology Letters 5:271-276,. 2013.
Lee SY,Park HS, Lee KY, Kim HJ,Jeon YJ,Jang TW,Lee KH,Kim YC,Kim KS,Oh IJ,Kim . Paclitaxel-SY.LoadedPolymericMicelle(230mg/m(2))andCisplatin(60mg/m(2))vs.Paclitaxel(175mg/m(2))andCisplatin(60mg/m(2))inAdvancedNon-Small-CellLungCancer:. AMulticenterRandomizedPhaseIIBTrialClinLungCancer. 2013:14(3):275-282 .
Lee JC, Jang SH, Lee KY, Kim YC. Treatment of Non-small Cell Lung Carcinoma after Failure of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor. Cancer Res Treat. 2013 Jun;45(2):79-85.
Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP. Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Proteomics. 2013 Jul;13(14):2125-34.
Kim YJ, Kim do Y, Seo JW, Lee SA, Hwang JJ, Kim HJ, Lee KY. A Case of Congenital Cystic Adenomatoid Malformation Infected with Mycobacterium avium-intracellulare Complex. Tuberc Respir Dis (Seoul). 2013 Jan;74(1):28-31 .
KH Lee, KY Lee, YJ Jeon, MH Jung, CH Son, YC Kim, SY Kim. Gefitinib in selected patients with pre-treated NSCLC : Result from a phase IV, multicenter, non-randomized study (SELINE). TuberRespirDis. 2012:73:303-311 .
HJ Kim, YC Kim, KS Kim, SY Lee, TW Jang, MK Lee, KC Shin, GH Lee, JE Lee, SY Kim. KY LEE. Detection and comparison of peptide nucleic acid-mediated real time polymerase chain reaction clamping and direct gene sequencing for epidermal growth factor receptor mutations in patients with non-small cell lung cancer. Lung Cancer. 2012:75;321-325 .
김희정, 김완섭, 신경철, 이관호, 김미진, 이정은, 송규상, 김선영, 이계영. EGFR 돌연변이 검출에 있어 PNA-Mediated Real-Time PCR Clamping과 직접 염기서열 분석법의 비교 분석. Tuberculosis and Respiratory Diseases. 2011:70;21-27 .
박유진, 박중희, 홍미진, 김원동, 이계영, 김순종, 김희정, 하경원, 전규락, 김현애, 유광하. 폐렴환자에서 진동 공명 영상 검사(VRI)의 유용성. Tuberculosis and Respiratory Diseases. 2011:71;31-36 .
Bae BJ, Kim HJ, Kim SJ, Lee KY, Kim WD, Yoo KH. A Case of Yellow Nail Syndrome: Misdiagnosis as Congestive Heart Failure. Tuberculosis and Respiratory Diseases. 2011:71:46-49 .
Ahn MH, Park BL, Lee SH, Park SW, Park JS, Kim DJ, Jang AS, Park JS, Shin HK, Uh ST, Kim YK, Kim YW, Han SK, Jung KS, Lee KY, Jeong SH, Park JW, Choi BW, Park IW, Chung MP, Shin HD, Song JW, Kim DS, Park CS, Shim YS. A promoter SNP rs4073T>A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode. Respir Res. 2011 Jun 8;12:73 .
Kye Young Lee. Molecular diagnosis in lung cancer. Journal of Lung Cancer. 2010;9:9-14 .
HS Park, SW Lee, SU Yun, BJ Bae, HJ Choi, SY Kim, HJ Choi, WS Kim, HJ Kim, KY Lee. Atypical thymoma (WHO Type B3) with neuroendocrine differentiation combined with hyperparathyroidism. Journal of Thoracic Oncology. 2010;5:1490-1491 .
KY Lee, HJ Kim, SJ Kim, GH Yoo, WD Kim, SY Oh, WS Kim. PNA-mediated PCR clamping for the detection of EGFR mutations in non-small cell lung cancer. Tuberc Respir Dis. 2010;69:271-278 .
Eon SY, Zhang YW, Kim SH, Choe KH, Lee KY, ParkJD ,HongYC, KimYD, KangWJ, KimH. Influence of NQO1, ALDH2, and CYP2E1 genetic polymorphisms, smoking, and alcohol drinking on the risk of the lung cancer in Korea. Cancer Causes Control. 2009:20:137-145 .
HJ Kim, KY LEE, ST Uh. Guideline of the Korean Academy of Medical Sciences for Assessing Respiratory Impairment. J Kor Med Science. 2009:24:S267-S270 .
Kye Young Lee. Target therapy in lung cancer. Journal of Korean Medical Association. 2008;51:483-491 .
PW Seo, KY Lee. The proteasome inhibitor MG132 sensitizes lung cancer cells to TRAIL-induced apoptosis by inhibiting NF-kB activation. Tuberc Respir Dis. 2008;65:476-486 .
KY Lee, JH Lee, SJ Kim, GH Yoo. Immunohistochemical analysis for the expression of DR5 TRAIL receptor and p53 in non-small cell lung cancer. Tuberc Respir Dis. 2008;64:278-284 .
Kim DH, Kim YS, Park JS, Kwon HJ, Lee KY, Lee SR, JeeYK. The effects of on-site ozone concentration on pulmonary function and symptoms of asthmatics. J Kor Med Science. 2007:22:30-36 .
KY LEE, JH Park, YJ Kim, Y So, JK Lee. Fibrosing mediatinitis manifesting as thoracic prevertebral thin band-like mass on MRI and PET-CT. British J Radiology. 2007:80-141-144 .
Kim DL, Song KH, Lee JH, Lee KY, KimSK. Rifampin-inducd hypothyroidism without underlying thyroid disease. Thyroid. 2007:17:793-795 .
JH Kim, H Kim, KY Lee, JW Kang, KH Lee, SY Park, HI Yoon, SH Jeon, SW Sung, YC Hong. Aryl hydrocarbon receptor gene polymorphsm affect lung cancer risk. Lung Cancer. 2007, 56:9-15 .
JH Kim, H Kim, KY Lee, KH Choe, JS Ryu, HI Yoon, SW Sung, KY Yoo, YC Hong. Genetic polymorphi는 of ataxia telangiectasia mutated affect lung cancer risk. Human Molecular Genetics. 2006 15:1181-1186 .
YS Kim, JS Park, YK Jee, KY Lee. Dexamethasone inhibits TRAIL-and anti-cancer drugs-induced cell death in A549 cells through inducing NF-kB-independent cIAP2 expression. Cancer Research and Treatment. 2004;36:330-337 .
EK Choi, JS Park, YK Jee, KY Kim, KY LEE. The role of pleural mesothelial cells and the mechanism of IL-8 secretion in tuberculous pleurisy. Scandinavian J Immunology. 2003;57: 463-469 .
Lee KY, JS Park, YK Jee, Rosen GD. Triptolide sensitizes lung cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by inhibition of NF-κB activation. Experimental Molecular Med. 2002; 34:462-468 .
Jung JH, Lee MG, Cho SH, Kim YC, Park HJ, Cinn YW, Lee KY. ImmunohistochemicalAnalysisforBasalActivationofNF-κBinAcralLentiginousMelanoma. AnnalsDermatology. 2002;14:189-194 .
Kim DH, Lee JH, Kim BH, Choi EK, Park JS, Kim KY, Choi YH, MyongNH, Lee KY. Chronic Necrotizing Bronchopulmonary Aspergilosis with elements of Bronchocentric Granulomatosis. Kor J Int Med. 2002;17:138-142 .
Myong NH, Shin DH, Lee KY. A clinicopathologic study on three cases of constrictive bronchiolitis. J Kor Med Sci. 16:150-154,2001 .
Suk K, Kim YH, Chang I, Kim JY, Choi YH, Lee KY, Lee MS. IFNα sensitizes ME-180 human cervical cancer cells to TNFα-induced apoptosis by inhibiting cytoprotective NF-κB activation. FEBS Letters 495:66-70,. 2001.
Chang WT, Kang JJ, Lee KY, Wei K, Anderson E, Gotmare S, Ross JA, Rosen GD. Triptolide and chemotherapy cooperate in tumor cell apoptosis: a role for the p53 pathway. J Biol Chem. 276:2221-2227,2001 .
YH Kim, NY Kwon, NH Myong, EJ Kim, YH Choi, SY Yoon, EK Choi, JS Park, KY Kim, KY Lee. A Case of Mediastinal Angiomyolipoma. Kor J Int Med. 2001:16:260-263 .
Choi YH, Im J-G, Han BK, Kim J-H, Lee KY, Myoung NH. Thoracic manifestation of Churg-Strauss syndrome: radiologic and clinical findings. Chest. 2000:117:117-124.
Choi YH, Kim SJ, Lee JY, Pai HJ, Lee KY, Lee YS. Scrub typhus: radiologic and clinical findings. Clin Radiol. 2000:55:140-144.
Jae Seok Park, Young Koo Jee, Kye Young Lee, Keun Youl Kim, NaHye Myong, PilWon Seo. Acute respiratory distress syndrome associated with scrub typhus : diffuse alveolar damage without pulmonary vasculitis. J Kor Med Science 15:343-345,. 2000.
Jee Y-K, Park H-S, Kim H-Y, Park J-S, Lee KY. KimK-Y, LeeM-H, KimYK, ChoSH, MinKU, KimYY. Two-spotted spidermite (Tetranychusurticae) allergy : Tetranychus urticae is an important allergen among asthmatic non-farmers exposed to this mite with summer and early fall season aggravation of asthmatic symptoms. Ann Allergy Asthma Immunol. 84:543-548,2000 .
Lee KY, Chang W, Qiu D, Kao PN, Rosen GD. PG490 (Triptolide) cooperates with tumor necrosis factor-α to induce apoptosis in tumor cells. J Biol Chem. 1999:274:13451-13455.
Lee KY, Anderson E, Madani K, Rosen GD. Loss of STAT1 expression confers resistance to IFN-γ-induced apoptosis in ME180 cells. FEBS Letters. 1999:459:323-326.
Park GY, Lee KY, YooCG, KimYW, HanSK, ShimYS. Bronchoscopic findings of endobronchial vascular lesions in patients with haemoptysis. Respirology. 1999:4:401-404.
Lee KY, Yoo C-G, Han SK, Shim Y-S, Kim YW. The effecs of transferring tumor suppressor gene p16INK4A to p16INK4A-deleted cancer cells. Kor J Int Med. 1999:14:53-58.